Synbio is a diverse field with diverse applications, and the different contexts (e.g., gain-of-function research, biofuels) raise different ethical and governance challenges. The objective of this course is to increase learners’ awareness and understanding of ethical and policy/governance issues that arise in the design, conduct and application of synthetic biology. The course will begin with a short history of recombinant DNA technology and how governance of that science developed and evolved, and progress through a series of areas of application of synbio.
Engineering Life: Synbio, Bioethics & Public Policy
Engineering Life: Synbio, Bioethics & Public Policy
Instructor: Debra JH Mathews, PhD, MA
8,251 already enrolled
Included with 
Gain insight into a topic and learn the fundamentals.
4.2
(78 reviews)
Intermediate level
Some related experience required
13 hours to complete
3 weeks at 4 hours a week
Flexible schedule
Learn at your own pace
Details to know
Shareable certificate
Add to your LinkedIn profile
Assessments
2 assignments
Taught in English
See how employees at top companies are mastering in-demand skills
Earn a career certificate
Add this credential to your LinkedIn profile, resume, or CV
Share it on social media and in your performance review
There are 6 modules in this course
What's included
1 video1 reading1 discussion prompt
We start the course by learning a bit about the history and context of the development of recombinant DNA (rDNA) technology in the 1970s, the ethics and policy issues raised by that science, and how those issues remain with us today in synthetic biology. The work of the week includes lecture videos, readings, and an interview with LeRoy Walters, who was involved in the discussions and debates about rDNA in its early years. The week will conclude with a quiz.
What's included
8 videos1 reading1 assignment1 discussion prompt
In Week 2 we will learn about and discuss gain of function (GOF) research and the dual-use concerns raised by synthetic biology. The work of the week includes lecture videos, a number of outside videos, and readings. The assessment this week will be your first peer-assessed project, and will focus on identifying ethical duties related to GOF research policy.
What's included
6 videos2 readings1 peer review2 discussion prompts
This week, we’ll learn about biofuels, the complex task of balancing the many ethical issues they raise, and the role of synthetic biology in biofuels development. The work of the week includes lecture videos, one outside video, readings, and an interview with Deborah Scott about biofuels governance. The week will conclude with a quiz.
What's included
7 videos2 readings1 assignment2 discussion prompts
This week we will learn a bit about applications of synthetic biology to human health, and the ethics of human subjects research. The work of the week includes lecture videos, one outside video, and readings. The assessment this week will be your second peer-assessed project, and will build on your first project, from Week 2. This project will focus on identifying stakeholders in a policy decision, their interests in the decision, and the related ethical duties of the decision-maker.
What's included
7 videos2 readings1 peer review2 discussion prompts
In the final week of the course, we will talk about both models of governance for emerging biotechnologies and the role of public engagement in the development and oversight of the science. The work of the week includes lecture videos, one outside video, and readings, as well as interviews with LeRoy Walters and Jane Calvert. The final course project builds on the Week 2 and 4 peer-assessed projects, and goes a step further, asking you to develop and defend a decision-making process for a government policy related to the release of genetically modified mosquitoes.
What's included
8 videos2 readings1 peer review2 discussion prompts
Instructor
Instructor ratings
4.7 (16 ratings)Offered by
Recommended if you're interested in Public Health
Duke University
University of Colorado Boulder
University of California San Diego
University of Illinois Urbana-Champaign
Why people choose Coursera for their career
Felipe M.
Learner since 2018
"To be able to take courses at my own pace and rhythm has been an amazing experience. I can learn whenever it fits my schedule and mood."
Jennifer J.
Learner since 2020
"I directly applied the concepts and skills I learned from my courses to an exciting new project at work."
Larry W.
Learner since 2021
"When I need courses on topics that my university doesn't offer, Coursera is one of the best places to go."
Chaitanya A.
"Learning isn't just about being better at your job: it's so much more than that. Coursera allows me to learn without limits."
Learner reviews
4.2
78 reviews
- 5 stars
60.25%
- 4 stars
19.23%
- 3 stars
6.41%
- 2 stars
3.84%
- 1 star
10.25%
Showing 3 of 78
AN
5
Reviewed on Sep 11, 2018
Dr. Matthews is a fantastic instructor; Slide deck is great.
JS
4
Reviewed on Nov 6, 2019
pretty good class. kind of technical but gives one some good stuff to think about
TN
5
Reviewed on Jun 15, 2017
Highly thought-provoking. One of the most interesting classes I have taken on Coursera.
New to Public Health? Start here.
Open new doors with Coursera Plus
Unlimited access to 10,000+ world-class courses, hands-on projects, and job-ready certificate programs - all included in your subscription
Advance your career with an online degree
Earn a degree from world-class universities - 100% online
Join over 3,400 global companies that choose Coursera for Business
Upskill your employees to excel in the digital economy
Frequently asked questions
The primary goal of this class is to help scientists think a bit more like policy makers and the public, seeing not only the incredible promise of the science they do, but also the potential risks and pitfalls, so these can be avoided or designed against at the beginning of a project, rather than at the end, when the challenges and costs are higher. Working with scholars, policy makers, and fellow learners, students will gain a greater understanding and appreciation of the ethics and governance of synthetic biology.
Access to lectures and assignments depends on your type of enrollment. If you take a course in audit mode, you will be able to see most course materials for free. To access graded assignments and to earn a Certificate, you will need to purchase the Certificate experience, during or after your audit. If you don't see the audit option:
The course may not offer an audit option. You can try a Free Trial instead, or apply for Financial Aid.
The course may offer 'Full Course, No Certificate' instead. This option lets you see all course materials, submit required assessments, and get a final grade. This also means that you will not be able to purchase a Certificate experience.
When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.