Our life is fine-controlled by various molecules in cells. Different types of molecules include macromolecules (e.g., protein, nucleic acid) and small molecules. In addition to classical views of central dogma, emerging roles of small molecules called metaboites have been recently proposed to significantly impact biological events. Metabolites are contiuously and dynamically produced by different metabolic pathways, thus playing key roles in energy metabolism as well as macromolecular biosynthesis/degradation. Accumulating evidence clearly suggests that certain types of metabolites exert signaling actions through interactions with macromolecules. Compared to other protein-protein and nucleic acid-protein interactions, metabolite-protein interactions appear significant in living cells, therby mediating specific actions in regulating target protein functions and activities.
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Ce que vous apprendrez
Learn about fundamental principles underlying various cellular signaling events controlled by endogenous small molecules
Compétences que vous acquerrez
- Catégorie : Cell Biology
- Catégorie : Biochemistry
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Instructeur
Recommandé si vous êtes intéressé(e) par Chemistry
Board Infinity
Imperial College London
Johns Hopkins University
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