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There are 6 modules in this course
The University of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences Drug Discovery course brings you lectures from both faculty and industry experts. With this course, recorded on campus at UCSD, we seek to share our access to top people in the field who bring an unprecedented range of expertise on drug discovery.
In this course you will learn the drug discovery process up to the filing of an Initial New Drug Application or IND. Each week you will learn the steps that a pharmaceutical or biotech company goes through to discover a new therapeutic drug. In this course you will be able to:
* Understand the pharmaceutical and biotechnology market a changing landscape
* Learn the major aspects of the drug discovery process, starting with target selection, to compound screening to designing lead candidates.
* Recognize current modern drug discovery based on the lock-and-key theory, which attempts to use one single compound to hit one target to combat the related disease.
* Increase understanding of the various drug discovery tools and methods that are used for finding, identifying and designing a new drug.
* Define and understand the regulatory responsibilities for drug discovery to file an Investigational New Drug Application (IND).
This course is intended as part 1 of a series: Drug Discovery, Drug Development (https://www.coursera.org/learn/drug-development) and Drug Commercialization (https://www.coursera.org/learn/drug-commercialization). We would highly recommend that you take the courses in order since it will give you a better understanding on how a drug is discovered in the lab before being tested in clinical trials and then launched in the market place.
What's included
1 video1 discussion prompt
Show info about module content
1 video•Total 3 minutes
Welcome!•3 minutes
1 discussion prompt•Total 10 minutes
Get to know your fellow Courserians!•10 minutes
Pharmaceutical & Biotechnology Industry Landscape
Module 2•2 hours to complete
Module details
In this module course lead Dr. Williams Ettouati begins by giving a landscape overview of the Pharma and Biotechnology landscape.
Global Outlook: What will the Future Look Like?•11 minutes
Creating a Sustainable Business•13 minutes
Patient-Centric Drug Discovery and Commercialization•9 minutes
A New Approach to R&D•10 minutes
Innovation and Its Role in Developing Better Drugs•7 minutes
3 readings•Total 15 minutes
Meet the Instructors•5 minutes
Lecture Slides•0 minutes
A new Master Degree in Science in Drug Development & Product Management at UCSD•10 minutes
1 assignment•Total 30 minutes
Pharma and Biotech•30 minutes
2 discussion prompts•Total 20 minutes
Mega-mergers: What are their implications?•10 minutes
Pharma and Biotech Changes•10 minutes
Drug Discovery: Proteomics, Genomics
Module 3•1 hour to complete
Module details
This week we will be hearing from Phillip Bourne, PhD. Dr. Bourne was, at the time of this recording, the Associate Vice Chancellor for Innovation and Industrial Alliances in the UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. Since that time, he has been named the first Associate Director for Data Science at the United States National Institutes of Health.
What's included
5 videos1 reading1 assignment1 discussion prompt
Show info about module content
5 videos•Total 50 minutes
Drug Discovery: Proteomics, Genomics I•10 minutes
Drug Discovery: Proteomics, Genomics II•12 minutes
Drug Discovery: Proteomics, Genomics III•9 minutes
Drug Discovery: Proteomics, Genomics IV•9 minutes
Drug Discovery: Proteomics, Genomics V•10 minutes
1 reading
Lecture Slides•0 minutes
1 assignment•Total 30 minutes
Drug Discovery: Proteomics, Genomics•30 minutes
1 discussion prompt•Total 10 minutes
What's the most interesting thing discussed this module?•10 minutes
Compound Selection & Preclinical Studies
Module 4•2 hours to complete
Module details
This week we will hear from Ronald Christopher, Ph.D. Dr. Ronald Christopher, Vice President of Preclinical Trials at Arena Pharmaceuticals.
Compound Selection and Pre-clinical Studies•30 minutes
2 discussion prompts•Total 20 minutes
Efforts in Drug Discovery: Differences between first-in-class and best-in-class•10 minutes
Develop your own first-in-class drug•10 minutes
Challenges in Fragment Based Drug Discovery for Protein Kinases
Module 5•2 hours to complete
Module details
In this module we will hear from Stephen Burley, M.D., Ph.D. At the time of this recording, Director of the Center for Integrative Proteomics at Rutgers University. He is now the Director of the Protein Data Bank and remains an Adjunct Professor at the UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences.
Challenges in Fragment Based Drug Discovery for Protein Kinases I•10 minutes
Challenges in Fragment Based Drug Discovery for Protein Kinases II•10 minutes
Challenges in Fragment Based Drug Discovery for Protein Kinases III•11 minutes
Challenges in Fragment Based Drug Discovery for Protein Kinases IV•10 minutes
Challenges in Fragment Based Drug Discovery for Protein Kinases V•9 minutes
2 readings•Total 3 minutes
Optional: Examples using structure based approaches•3 minutes
Lecture Slides•0 minutes
1 assignment•Total 30 minutes
Challenges in Fragment Based Drug Discovery for Protein Kinases•30 minutes
2 discussion prompts•Total 20 minutes
Collaboration among scientific disciplines - how important is it?•10 minutes
Clinical Trials Interruptions: What can we learn?•10 minutes
Key Concepts in Drug Delivery
Module 6•1 hour to complete
Module details
This module we hear from Professor of Clinical Pharmacy and Pediatrics, Brookie Best, Pharm. D., of UCSD's Skaggs School of Pharmacy and Pharmaceutical Sciences.
What's included
5 videos1 reading1 assignment1 discussion prompt
Show info about module content
5 videos•Total 47 minutes
Key Concepts in Drug Delivery I•9 minutes
Key Concepts in Drug Delivery II•10 minutes
Key Concepts in Drug Delivery III•10 minutes
Key Concepts in Drug Delivery IV•10 minutes
Key Concepts in Drug Delivery V•7 minutes
1 reading
Lecture Slides•0 minutes
1 assignment•Total 30 minutes
Concepts in Drug Delivery Quiz•30 minutes
1 discussion prompt•Total 10 minutes
How did this course help you?•10 minutes
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Instructors
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Learner since 2020
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Learner reviews
4.6
3,947 reviews
5 stars
71.24%
4 stars
24.04%
3 stars
3.64%
2 stars
0.55%
1 star
0.50%
Showing 3 of 3947
A
AD
5·
Reviewed on May 25, 2020
This course will help me in getting an idea about research for new drugs and site targets ,as well as which route is effective for administration of what type of drugs.
A
AG
5·
Reviewed on Nov 14, 2020
This course gives a very nice introduction into different considerations of drug development. Altough it is a bit older, I feel the topics are still relevant and up to date.
M
MK
5·
Reviewed on Nov 7, 2020
As a pharmaceutical sciences student, this course was extremely helpful and interesting, the materials covered answered many of the questions I had in regards to the topic !
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What will I get if I subscribe to this Specialization?
When you enroll in the course, you get access to all of the courses in the Specialization, and you earn a certificate when you complete the work. Your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile.
Is financial aid available?
Yes. In select learning programs, you can apply for financial aid or a scholarship if you can’t afford the enrollment fee. If fin aid or scholarship is available for your learning program selection, you’ll find a link to apply on the description page.