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Learner Reviews & Feedback for Epigenetic Control of Gene Expression by The University of Melbourne

4.8
stars
816 ratings

About the Course

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1 The course will re-open in 2022....

Top reviews

NN

Aug 1, 2021

This is the best course on coursera, 10/10. I wish it was longer and I could take it all over again. you will need background knowledge for this course but it is an amazing course and I will miss it.

MM

Oct 1, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

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201 - 225 of 226 Reviews for Epigenetic Control of Gene Expression

By Daniel S

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Nov 14, 2016

Excelent!

By 19BBT041_Praveen.R

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May 20, 2020

The best

By Carlos E

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Sep 22, 2017

Amazing!

By Ilir S

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Dec 1, 2017

Awesome

By Fall A

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Oct 12, 2017

good .

By aya s

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May 2, 2019

great

By Daniel F R R

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Apr 25, 2016

Nicee

By Hu N

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Feb 16, 2019

nice

By Anubhav C

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Jun 12, 2018

This is an excellent introductory course in epigenetics, however, if the course had included few chapters in epigenetic modifications like acetylation, glycosylation, phosphorylation, etc. it would have been much more exciting. Nevertheless, the course is extremely lucid to follow, the tutoring is really insightful, the materials are well-structured, the instructions are well-laid and, the most importantly, the assignments are challenging.

By Cristian C

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May 9, 2023

It was an interesting course, although, I would have preferred a better explanation of terms used in this course. Anywawy, overall, it is an excellent course which gives you an insight into Epigenetics

By Alberto T

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Jun 23, 2016

Very clear explanations. Four star because I think that the part on X chromosome is too long and covered with too details respect to other topics.

By Sohaila J

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May 27, 2017

Loved it. Very well structured and explained. I actually looked forward to completing lectures and readings every week.

By Jayne G

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Aug 31, 2016

I really enjoyed this course, and as an Australian it is so exciting it comes form a domestic university. Thank you

By Louis-Stéphane I L C

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May 29, 2020

Very interesting course covering many diverse aspects regarding epigenetics. Has been invaluable towards my PhD!

By MEENA M 1

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May 18, 2020

The course was really very informative. But it would have been great if the subject was little more simplified.

By 丁雪松

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Dec 1, 2016

this course gave a general ideal about epigenetic control, and it is helpful to me, Thanks

By Theodor S

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Dec 7, 2017

Very useful course for anyone who wants to get a deeper understanding of epigentics.

By ubaid m

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May 7, 2017

this course too me to the highest of my knowledge. i think this course is remarkable

By Echefu B E

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Jul 13, 2023

This is the right course towards gaining deep insight about epigenetics

By Renate L

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Oct 21, 2021

sehr gute Inhalte, die Übersetzung ist nicht immer bestens

By Yvonne A

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Sep 22, 2016

Difficult course but very worthwhile your time

By Joana A d S

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May 20, 2020

Very interesting and helpful!

By Zhimin L

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Apr 18, 2016

Interesting & Professional.

By EDavid L

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Nov 12, 2024

It is a very interesting subject and very necessary to learn nowadays when studying anything with genetics as it relates profoundly. But it should have been updated a while ago. I did it in 2020 which is fine but for 2024 it's not a good idea since even for 2020 it was not up to date and this field has changed a lot with new techniques and all.

By El-Cheikh F K

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Aug 8, 2023

The course could have been much better. The Professor's teaching does not show any passion, it could have been taught in a much better way. The examples could have been delivered in a simpler way. There wasn't much focus on acetylation, phosphorylation and ubiquitination. Don't take this course.