Last week, we built our Deep Learning foundation, learning about perceptrons and the backprop algorithm. This week, we are learning about optimization methods. We will start with Stochastic Gradient Descent (SGD). SGD has several design parameters that we can tweak, including learning rate, momentum, and decay. Then we will turn our attention to advanced gradient descent methods like learning rate scheduling and Nesterov momentum. Besides vanilla gradient descent, other optimization algorithms include AdaGrad, AdaDelta, RMSprop, and Adam. We will cover general tips to reduce overfitting while training neural networks, including regularization methods like dropout and batch normalization. This week, you will build your DL toolkit, gaining experience with the Python library Keras. Assessments for the week include a quiz and a Jupyter lab notebook with an accompanying Peer Review. This assignment is your last Jupyter lab notebook for the course. For the next three weeks, you will build hands-on experience and complete weekly mini-projects that incorporate Kaggle challenges.

This module will teach a type of neural network called convolutional neural networks, suitable for image analysis tasks. We will learn about definitions, design parameters, operations, hyperparameter tuning, and applications. There is no Jupyter lab notebook this week. You will have a brief quiz and participate in a clinically relevant Kaggle challenge mini-project. It is critical to evaluate whether cancer has spread to the sentinel lymph node for staging breast cancer. You will build a CNN model to classify whether digital pathology images show that cancer has spread to the lymph nodes. This project utilizes the PCam dataset, which has an approachable size, with the authors noting that "Models can easily be trained on a single GPU in a couple of hours, and achieve competitive scores." As you prepare for the week, look over the rubric and develop a plan for how you will complete it. It will be necessary for a project like this to work on a timeframe that allows you to run experiments. The expectation is not that you will cram the equivalent of a final project into a single week or that you need to have a top leaderboard score to receive a good grade for this project. Hopefully, you will have time to achieve some exciting results to show off in your portfolio.

This module will teach you another neural network called recurrent neural networks (RNNs) to handle sequential data. So far, we have covered feed-forward neural networks, including Multi-layer Perceptrons and CNNs. However, in biological systems, information can flow backward and forwards. RNNs do a backward pass closer to biological systems. Using RNNs has excellent benefits, especially for text data, since RNN architectures reduce the number of parameters. We will learn about the vanishing and exploding gradient problems that can arise when working with vanilla RNNs and remedies for those problems, including GRU and LSTM cells. We don't have a quiz this week, but we have a Kaggle challenge mini-project on NLP with Disaster Tweets. The project is a Getting Started competition designed for learners building their machine learning background. The challenge is very doable in a week, but make sure to start early to run experiments and iterate a bit.

This module will focus on neural network models trained via unsupervised Learning. We will cover autoencoders and GAN as examples. We will consider the famous AI researcher Yann LeCun's cake analogy for Reinforcement Learning, Supervised Learning, and Unsupervised Learning. Supervised Deep Learning has had tremendous success, mainly due to the availability of massive datasets like ImageNet. However, it is expensive and challenging to obtain labeled data for areas like biomedical images. There is great motivation to continue developing unsupervised Deep Learning approaches to harness abundant unlabeled data sources. This week is the last week of new course material. There is no quiz or Jupyter notebook lab. Generative adversarial networks (GANs) learn to generate new data with the same statistics as the training set. This week, you will wrap up one final Kaggle mini-project. This time, you will experiment with creating a network to generate images of puppies.