This course will cover the topic of Whole genome sequencing (WGS) of bacterial genomes which is becoming more and more relevant for the medical sector. WGS technology and applications are high on international political agenda, as the classical methods are being replaced by WGS technology and therefore bioinformatic tools are extremely important for allowing the people working in this sector to be able to analyze the data and obtain results that can be interpreted and used for different purposes. The course will give the learners a basis to understand and be acquainted with WGS applications in surveillance of bacteria including species identification, typing and characterization of antimicrobial resistance and virulence traits as well as plasmid characterization. It will also give the opportunity to learners to learn about online tools and what they can be used for through demonstrations on how to use some of these tools and exercises to be solved by learners with use of freely available WGS analysis tools .
Whole genome sequencing of bacterial genomes - tools and applications
Instructors: Lina Cavaco
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There are 5 modules in this course
Welcome and introduction to typing of bacteria and use of Whole genome sequencing applied to surveillance of bacterial pathogens and antimicrobial resistance
What's included
3 videos1 assignment1 discussion prompt
Introduction to Next Generation sequencing
What's included
3 videos1 assignment
Whole genome sequencing tools- demonstration of analysis tools for species identification, MLST typing and finding resistance genes
What's included
3 videos1 assignment
Whole genome sequencing tools- demonstration of analysis tools for Serotyping of Salmonella and Escherichia coli strains , and finding plasmid replicons
What's included
4 videos1 assignment
Whole genome sequencing tools- demonstration of analysis tools for multiple analyzes, phylogenetic tree building and finding genetic markers from self-made databases and Summative Tutorial exercise
What's included
5 videos1 reading2 assignments
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University of Leeds
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Reviewed on Apr 22, 2024
This is an interesting course. I do not have any prior knowledge of bioinformatics but I was able to understand with constant practice. Thank you DTU! Thank you, Coursera!!!
Reviewed on Sep 30, 2018
This course helped me a lot in determining bacterial typing. Just one question, in some quizzes I got some answers wrong so is there any way of knowing the right answer.
Reviewed on Apr 2, 2020
A well structured course covering a broad range of topics, and being a part of this course was an amazing learning experience..
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