Back to Genomic Data Science and Clustering (Bioinformatics V)
University of California San Diego

Genomic Data Science and Clustering (Bioinformatics V)

How do we infer which genes orchestrate various processes in the cell? How did humans migrate out of Africa and spread around the world? In this class, we will see that these two seemingly different questions can be addressed using similar algorithmic and machine learning techniques arising from the general problem of dividing data points into distinct clusters. In the first half of the course, we will introduce algorithms for clustering a group of objects into a collection of clusters based on their similarity, a classic problem in data science, and see how these algorithms can be applied to gene expression data. In the second half of the course, we will introduce another classic tool in data science called principal components analysis that can be used to preprocess multidimensional data before clustering in an effort to greatly reduce the number dimensions without losing much of the "signal" in the data. Finally, you will learn how to apply popular bioinformatics software tools to solve a real problem in clustering.

Status: Unsupervised Learning
Status: Data Analysis Software
IntermediateCourse10 hours

Featured reviews

MK

5.0Reviewed Nov 10, 2018

Absolutely fantastic course. Kudos to the course creators.

DD

5.0Reviewed Oct 23, 2019

Truly awesome. What I liked best was that this course didn't have a peer reviewed final challenge, so I didn't have to wait months until my work was graded :)

ZX

5.0Reviewed Jul 20, 2019

In depth and comprehensive coverage of the topics in genetic data analysis.

HW

5.0Reviewed Jun 9, 2017

the part about EM is the best I know, and first time I understand the EM algorithm.

JM

5.0Reviewed Mar 21, 2020

Really enjoyed the clustering chapters and the practical exercises with the yeast dataset

All reviews

Showing: 20 of 23

Zack Xu
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Reviewed Jul 21, 2019
Michael Kessler
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Reviewed Nov 11, 2018
Yasmine El Hajj
4.0
Reviewed Jul 23, 2020
prachi
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Reviewed Aug 12, 2020
Ho Yin Chan
2.0
Reviewed Jul 26, 2019
Mark Joselli
1.0
Reviewed Sep 28, 2017
Ahmet Can Boyraz
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Reviewed Feb 2, 2018
MILK ZHENG
5.0
Reviewed Feb 3, 2019
Daniel Danciu
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Reviewed Oct 24, 2019
Erika Lorena Álvarez Ramírez
5.0
Reviewed Jun 22, 2017
Maksym Kovalchyk
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Reviewed May 15, 2020
Jason Moggridge
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Hao Wu
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Pavel Oliynyk
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Reviewed Apr 1, 2020
Ahmad Mohammed Yusuf Alaghbary
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Reviewed Dec 20, 2017
Mihai Alexandru-Ionut
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Reviewed Jan 12, 2018
­박준형 / 학생 / 컴퓨터공학부
5.0
Reviewed Sep 13, 2018
Sakshar Chakravarty
4.0
Reviewed Jun 16, 2020
Qiyue Wang
4.0
Reviewed May 22, 2017
Ashwin Somalinga Suresh
4.0
Reviewed Aug 10, 2023