What you will learn

• Identify the relationship between models and real-world epidemiological data

• Incorporate treatment or vaccination into an SIR model, accounting for imperfect efficacy, and for different mechanisms of action

• Perform simple calibrations of an SIR model against time-series data, selecting parameters to maximise the fit of the model to the data

• Recognise two simple approaches to computer-based model calibration and perform model calibrations under each of these approaches in R.