This course describes the underpinning science around vaccines and their development. It will look at the immunological underpinnings of how vaccines induce protection. It will also look at the epidemiological basis of how vaccines are rolled out. Finally it will explore how new vaccines are developed.
How Vaccines Work
Ce cours fait partie de Spécialisation Foundations in Virology and Vaccinology
Instructeur : John Tregoning
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(25 avis)
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Ce que vous apprendrez
Recognise how viruses cause infections
Recognise how vaccines prevent infections
Compétences que vous acquerrez
- Catégorie : Describe how we can detect, identify and track viruses in individuals and populations
- Catégorie : Identify the features of different vaccine platforms
- Catégorie : Recognise how transmission drives virus pathogenesis and shapes virus evolution
- Catégorie : Understand how the immune response mediates vaccine protection
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Il y a 4 modules dans ce cours
Basic overview of the immune system. This will cover: what is the immune system, what is immune memory, why that is important for vaccines, the key cells of adaptive immunity and then how these all contribute to vaccine induced protection.
Inclus
9 vidéos7 lectures1 devoir
This module will cover vaccines at a population level introducing some epidemiological principles. We will explore how infections spread (and how we model that). We will introduce the role of herd immunity. We will discuss what pathogen eradication means and what types of disease are eradicable and which ones are not?
Inclus
6 vidéos4 lectures1 devoir2 sujets de discussion
Novel vaccines are no use if they are stuck on the shelves of research labs, they need to be deployed to prevent infections. Here, we will explore the process of clinical trials which test vaccines for safety and efficacy (whether they work), we will look at ways to measure vaccine success. Then move onto how vaccines are made and how they are deployed.
Inclus
6 vidéos5 lectures1 devoir3 sujets de discussion
As we have seen during the COVID-19 pandemic, there is a need for new vaccines. But it isn’t just for novel emerging diseases. There are a whole host of endemic infections that would benefit from new vaccines. With changing population dynamics and climate change, different disease profiles would benefit from vaccines. Here, we will explore why we might need new vaccines. We will look what an ideal vaccine might look like, and the scientific challenges in developing one. We will then look at the real-world challenges that prevent uptake and deployment of such a vaccine, both logistic and societal.
Inclus
6 vidéos5 lectures1 devoir3 sujets de discussion
Instructeur
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Recommandé si vous êtes intéressé(e) par Basic Science
University of Toronto
Johns Hopkins University
American Museum of Natural History
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Avis des étudiants
25 avis
- 5 stars
96 %
- 4 stars
4 %
- 3 stars
0 %
- 2 stars
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- 1 star
0 %
Affichage de 3 sur 25
Révisé le 18 déc. 2024
A good synopsis for the early investigator in vaccinology. A "blast into the past" & review for others. But well worth the effort to both.
Révisé le 13 août 2024
Excellent really enjoying, easy to understand and navigate thankyou
Révisé le 4 juil. 2024
Excelente opción para adentrarte al entendiemiento de las vacunas, te lleva de la mano y puntualiza los conceptos básicos.
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