This course explores the different types of vaccine available. This is a useful framework for understanding the scientific understanding that went into vaccine development. It also gives a perspective of how innovation (e.g. fundamental virology, molecular biology) work in a translational medicine context.
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Types of Vaccine
Ce cours fait partie de Spécialisation Foundations in Virology and Vaccinology
Instructeur : John Tregoning
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(12 avis)
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Ce que vous apprendrez
Recognise how viruses cause infections
Recognise how vaccines prevent infections
Compétences que vous acquerrez
- Catégorie : Describe how we can detect, identify and track viruses in individuals and populations
- Catégorie : Identify the features of different vaccine platforms
- Catégorie : Recognise how transmission drives virus pathogenesis and shapes virus evolution
- Catégorie : Understand how the immune response mediates vaccine protection
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Il y a 4 modules dans ce cours
First, we will look at the very first vaccines and how they shaped the future of the field. This shows how vaccine development closely follows developments in other scientific fields. The early history of microbiology and vaccinology are closely tied. The founders of one field often worked in another – for example Louis Pasteur and Robert Koch. Their approaches centred on the whole pathogen. Early vaccines were made with an understanding of infection biology, but not so much about the immune response to these pathogens. We will focus in on the range of methods used to develop vaccines, many of which are still used in vaccine development today.
Inclus
6 vidéos7 lectures1 devoir2 sujets de discussion
Here we will look at protein and sugar-based vaccines. We will start by looking at how these vaccines provide protection. We will then investigate how novel biotechnology techniques have helped in the development of new vaccines, before looking at how sugars can be targeted and the impact this has had. Finally, we will explore how advances in immunological understanding are helping to shape the next generation of vaccines.
Inclus
5 vidéos3 lectures1 devoir4 sujets de discussion
Here we will explore how instead of targeting individual parts of a pathogen, we can take weaker forms of a pathogen and use it to make a vaccine. We will look at the original vaccines that were developed by this approach, then more broadly at how the immune system provides protection at two sites of infection – the airways and the guts. Finally, we will look at two viral pathogens, polio and influenza, and the past, present and future of vaccines for them.
Inclus
5 vidéos3 lectures1 devoir2 sujets de discussion
Finally, we will look at how vaccines can be used to prevent and contain pandemics. We will start with a history of the use of vaccines in pandemics and the special requirements. We will then look at two of the new platforms that were successful during the COVID-19 pandemic, RNA and viral vectors.
Inclus
6 vidéos4 lectures1 devoir3 sujets de discussion
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