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    Johns Hopkins University
    Introduction to the Biology of Cancer
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    • Outcomes
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    2. Health
    3. Basic Science
    Johns Hopkins University

    Introduction to the Biology of Cancer

    This course is part of Cancer Biology Specialization

    Kenneth J. Pienta, M.D.

    Instructor: Kenneth J. Pienta, M.D.

    213,607 already enrolled

    Included with Coursera Plus

    •Learn more
    6 modules
    Gain insight into a topic and learn the fundamentals.
    4.8

    (7,629 reviews)

    Beginner level
    No prior experience required
    Flexible schedule
    Approx. 8 hours
    Learn at your own pace
    97%
    Most learners liked this course

    6 modules
    Gain insight into a topic and learn the fundamentals.
    4.8

    (7,629 reviews)

    Beginner level
    No prior experience required
    Flexible schedule
    Approx. 8 hours
    Learn at your own pace
    97%
    Most learners liked this course
    • About
    • Outcomes
    • Modules
    • Recommendations
    • Testimonials
    • Reviews

    Skills you'll gain

    • Clinical Research
    • Epidemiology
    • Treatment Planning
    • Anatomy
    • General Science and Research
    • Image Analysis
    • Life Sciences
    • General Medical Tests and Procedures
    • Medical Science and Research
    • Risk Analysis

    Details to know

    Shareable certificate

    Add to your LinkedIn profile

    Assessments

    7 assignments

    Taught in English

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    Build your subject-matter expertise

    This course is part of the Cancer Biology Specialization
    When you enroll in this course, you'll also be enrolled in this Specialization.
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    There are 6 modules in this course

    Over 500,000 people in the United States and over 8 million people worldwide are dying every year from cancer. As people live longer, the incidence of cancer is rising worldwide and the disease is expected to strike over 20 million people annually by 2030. This open course is designed for people who would like to develop an understanding of cancer and how it is prevented, diagnosed, and treated.

    The course introduces the molecular biology of cancer (oncogenes and tumor suppressor genes) as well as the biologic hallmarks of cancer. The course also describes the risk factors for the major cancers worldwide, including lung cancer, breast cancer, colon cancer, prostate cancer, liver cancer, and stomach cancer. We explain how cancer is staged, the major ways cancer is found by imaging, and how the major cancers are treated. In addition to the core materials, this course includes two Honors lessons devoted to cancers of the liver and prostate. Upon successful completion of this course, you will be able to: - Identify the major types of cancer worldwide. (Lecture 1) - Describe how genes contribute to the risk and growth of cancer. (Lecture 2) - List and describe the ten cellular hallmarks of cancer. (Lecture 3) - Define metastasis, and identify the major steps in the metastatic process. (Lecture 4) - Describe the role of imaging in the screening, diagnosis, staging, and treatments of cancer. (Lecture 5) - Explain how cancer is treated. (Lecture 6) We hope that this course gives you a basic understanding of cancer biology and treatment. The course is not designed for patients seeking treatment guidance – but it can help you understand how cancer develops and provides a framework for understanding cancer diagnosis and treatment.

    In this first week, we'll get a high-level introduction to the basics of cancer biology as well as incidence and common types of cancer.

    What's included

    5 videos4 readings1 assignment

    5 videos•Total 47 minutes
    • Welcome to the Course•3 minutes•Preview module
    • Incidence and Etiology Overview•0 minutes
    • Incidence and Etiology of Cancer•10 minutes
    • Cancer Incidence•4 minutes
    • The Common Cancers•29 minutes
    4 readings•Total 40 minutes
    • Welcome•10 minutes
    • Grading and Honors Lesson•10 minutes
    • Suggested Reading List•10 minutes
    • Pre-Course Survey•10 minutes
    1 assignment•Total 30 minutes
    • Introduction Quiz•30 minutes

    Now, we'll turn our attention to the genetics of cancer, variation and mutation, two-hit hypothesis, and genomic instability.

    What's included

    4 videos1 assignment

    4 videos•Total 16 minutes
    • Genetics Overview•1 minute•Preview module
    • Basic Introduction to Genetics•5 minutes
    • Genetic Variation and Mutation•3 minutes
    • Two-Hit Hypothesis and Genomic Instability•6 minutes
    1 assignment•Total 30 minutes
    • Genetics Quiz•30 minutes

    All cancers share ten cellular hallmarks. This week, you'll learn to identify these hallmarks in order to distinguish a normal cell from a cancerous cell.

    What's included

    4 videos1 assignment

    4 videos•Total 36 minutes
    • Cellular Hallmarks Overview•1 minute•Preview module
    • The Human Cell and Hallmarks of Cancer 1-5•16 minutes
    • The Human Cell and Cellular Hallmarks Cancer 6-8•8 minutes
    • Cellular Hallmarks of Cancer 9 & 10: Preparing the Cancer Cell to Move and Metastasize•10 minutes
    1 assignment•Total 30 minutes
    • Hallmarks Quiz•30 minutes

    The lethal agent of cancer is metastasis. This week, we'll take a good look at this deadly event, TNM staging, the metastatic process, and an ecological paradigm.

    What's included

    5 videos1 assignment

    5 videos•Total 32 minutes
    • Metastasis Overview•1 minute•Preview module
    • Introduction to Metastasis•6 minutes
    • TNM Staging•5 minutes
    • The Metastatic Process•12 minutes
    • An Ecological Paradigm: Why Do Cancer Cells Metastasize from the Primary Tumor?•5 minutes
    1 assignment•Total 30 minutes
    • Metastasis Quiz•30 minutes

    This week, we'll examine imaging as a tool for diagnosis, staging, and treatment of cancer.

    What's included

    5 videos1 assignment

    5 videos•Total 37 minutes
    • Imaging Overview•1 minute•Preview module
    • Introduction to Imaging•8 minutes
    • Types of Imaging•7 minutes
    • Imaging in Clinical Oncology•14 minutes
    • Theory of Oligometastasis and How Treatment is Supported by Imaging•5 minutes
    1 assignment•Total 30 minutes
    • Imaging Quiz•30 minutes

    In this final week, we'll examine the variety of treatment options available to doctors and patients as well as the features of clinical trials and how they are used to improve the treatment arsenal.

    What's included

    9 videos1 reading2 assignments

    9 videos•Total 53 minutes
    • Treatment Overview•0 minutes•Preview module
    • Types of Treatment•15 minutes
    • Types of Treatments for Individual Cancers•14 minutes
    • Clinical Trials•3 minutes
    • Wrap-Up•1 minute
    • Liver Cancer Overview•0 minutes
    • Incidence, Risk Factors, Screening•7 minutes
    • Staging For Liver Cancer•3 minutes
    • Treatment of Liver Cancer•5 minutes
    1 reading•Total 10 minutes
    • Post-Course Survey•10 minutes
    2 assignments•Total 60 minutes
    • Treatment Quiz•30 minutes
    • Liver Cancer Quiz•30 minutes

    Instructor

    Instructor ratings

    Instructor ratings

    We asked all learners to give feedback on our instructors based on the quality of their teaching style.

    4.8 (1,642 ratings)
    Kenneth J. Pienta, M.D.
    Kenneth J. Pienta, M.D.
    Johns Hopkins University
    3 Courses•243,245 learners

    Offered by

    Johns Hopkins University

    Offered by

    Johns Hopkins University

    The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.

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    Why people choose Coursera for their career

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    4.8

    7,629 reviews

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    5

    Reviewed on Jun 16, 2022

    I am Traditional Tibetan physician this couse is exellent and it's really helpful to me gaining lots of new knowledage about cancer biology .I am looking forward to learn more things.

    S
    SS
    5

    Reviewed on Apr 11, 2019

    Thanks a lot, Dr. Kenneth; the course has been very informative and mind-opening--it has also whetted my appetite to learn more about the topic.Thanks and best of regards in your endeavours!

    F
    FA
    5

    Reviewed on Jun 5, 2020

    It was a course of much interest. Everything is explained very simply. I have learned lot of important information. I am delighted to be able to do this online course at JOHNS HOPIKNS university.

    View more reviews

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