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This course is part of Cancer Biology Specialization
Instructor: Kenneth J. Pienta, M.D.
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Over 500,000 people in the United States and over 8 million people worldwide are dying every year from cancer. As people live longer, the incidence of cancer is rising worldwide and the disease is expected to strike over 20 million people annually by 2030. This open course is designed for people who would like to develop an understanding of cancer and how it is prevented, diagnosed, and treated.
The course introduces the molecular biology of cancer (oncogenes and tumor suppressor genes) as well as the biologic hallmarks of cancer. The course also describes the risk factors for the major cancers worldwide, including lung cancer, breast cancer, colon cancer, prostate cancer, liver cancer, and stomach cancer. We explain how cancer is staged, the major ways cancer is found by imaging, and how the major cancers are treated. In addition to the core materials, this course includes two Honors lessons devoted to cancers of the liver and prostate. Upon successful completion of this course, you will be able to: - Identify the major types of cancer worldwide. (Lecture 1) - Describe how genes contribute to the risk and growth of cancer. (Lecture 2) - List and describe the ten cellular hallmarks of cancer. (Lecture 3) - Define metastasis, and identify the major steps in the metastatic process. (Lecture 4) - Describe the role of imaging in the screening, diagnosis, staging, and treatments of cancer. (Lecture 5) - Explain how cancer is treated. (Lecture 6) We hope that this course gives you a basic understanding of cancer biology and treatment. The course is not designed for patients seeking treatment guidance – but it can help you understand how cancer develops and provides a framework for understanding cancer diagnosis and treatment.
In this first week, we'll get a high-level introduction to the basics of cancer biology as well as incidence and common types of cancer.
5 videos4 readings1 assignment
Now, we'll turn our attention to the genetics of cancer, variation and mutation, two-hit hypothesis, and genomic instability.
4 videos1 assignment
All cancers share ten cellular hallmarks. This week, you'll learn to identify these hallmarks in order to distinguish a normal cell from a cancerous cell.
4 videos1 assignment
The lethal agent of cancer is metastasis. This week, we'll take a good look at this deadly event, TNM staging, the metastatic process, and an ecological paradigm.
5 videos1 assignment
This week, we'll examine imaging as a tool for diagnosis, staging, and treatment of cancer.
5 videos1 assignment
In this final week, we'll examine the variety of treatment options available to doctors and patients as well as the features of clinical trials and how they are used to improve the treatment arsenal.
9 videos1 reading2 assignments
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The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
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Yale University
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Reviewed on Jun 16, 2022
I am Traditional Tibetan physician this couse is exellent and it's really helpful to me gaining lots of new knowledage about cancer biology .I am looking forward to learn more things.
Reviewed on Apr 11, 2019
Thanks a lot, Dr. Kenneth; the course has been very informative and mind-opening--it has also whetted my appetite to learn more about the topic.Thanks and best of regards in your endeavours!
Reviewed on Jun 5, 2020
It was a course of much interest. Everything is explained very simply. I have learned lot of important information. I am delighted to be able to do this online course at JOHNS HOPIKNS university.
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Access to lectures and assignments depends on your type of enrollment. If you take a course in audit mode, you will be able to see most course materials for free. To access graded assignments and to earn a Certificate, you will need to purchase the Certificate experience, during or after your audit. If you don't see the audit option:
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When you enroll in the course, you get access to all of the courses in the Specialization, and you earn a certificate when you complete the work. Your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.
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