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Learner Reviews & Feedback for Lead Selection & Optimization by Novartis

4.9
stars
19 ratings

About the Course

This course covers the stages of drug discovery in which promising compounds (leads) are identified, their optimal and suboptimal
characteristics determined, and the suboptimal characteristics optimized to create a candidate suitable for the clinic.  The course is built around
a case study on the discovery of an antimalarial therapy.  Assays useful for screening new compounds are outlined, examples of selection
criteria for leads are discussed - such as potency, efficacy, and pharmacokinetics - and the structure activity relationships that contribute to the
optimization of a lead series are considered.  The phenotypic approach used by the antimalarial program will be briefly contr...
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Top reviews

GS

Nov 30, 2024

It is a perfect course with ample knowledge and testing of knowledge by quizzes and discussions.

EK

Sep 3, 2024

Key concepts covered in a concise and accessible format.

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1 - 3 of 3 Reviews for Lead Selection & Optimization

By Gaurang S

•

Dec 1, 2024

It is a perfect course with ample knowledge and testing of knowledge by quizzes and discussions.

By Elaina K

•

Sep 4, 2024

Key concepts covered in a concise and accessible format.

By jsingh017

•

Dec 12, 2024

Excellent and informative